For over a year now, I have had the Nook Color, and I am very pleased with the e-reader, so this year I upped the game and bought the tablet version of Nook. The OS and feel is exactly the same except the hardware inside is vastly improved. It's quicker and more responsive than the Nook Color and can do more with the applications that can be put on it. The biggest improvement I see with the tablet version of the Nook is the anti-glare screen. I know this can be achieved by buying an anti-glare screen guard, but who wants that on the Nook. I sure don't.
Anyway this wasn't for me, it was for my wife and she loves it. All the Nook needs is a better selection of apps. As an e-reader, this is number 1, and Barnes and Noble seems to have more and more e-books daily.
In addition to using the bn website to buy books, you can go to site like ManyBooks, or if you are a sci-fi junkie try the Baen free library. The thing I really like about my Nook, is that I can use it at my local library as well! I can just check out my e-book from anywhere as long as I have my library card.
The issue I really do not like about any tablet/reader is the virtual keyboard, but that's even an issue for the sacred iPad.